| 1 | Welcome; Introduction and course organization | |
| 2 | Chemical bonding and molecular interactions; Lipids and membranes | |
| 3 | Structures of amino acids, peptides and proteins | |
| 4 | Enzymes and metabolism | |
| 5 | Carbohydrates and glycoproteins | Problem set 1 due |
| 6 | Nucleic acids | |
| 7 | Replication | |
| 8 | Transcription | |
| 9 | Chromatin remodeling and splicing | |
| 10 | Translation | Problem set 2 due |
| 11 | Cells, the simplest functional units | |
| Exam 1 (Covering Lectures 1–10) |
| 12 | Genetics 1—Cell division and segregating genetic material | |
| 13 | Genetics 2—Rules of inheritance | |
| 14 | Genetics 3—Linkage, crossing over | Problem set 3 due |
| 15 | Genetics 4—The power of model organisms in biological discovery | |
| 16 | Recombinant DNA, cloning, and editing | |
| 17 | Genomes and DNA sequencing | |
| 18 | SNPs and human genetics | Problem set 4 due |
| Exam 2 (Covering Lectures 11–17) |
| 19 | Cell trafficking and protein localization | |
| 20 | Cell signaling 1—Overview | |
| 21 | Cell signaling 2—Examples | |
| 22 | Neurons, action potential, and optogenetics | |
| 23 | Cell cycle and checkpoints | |
| 24 | Stem cells, apoptosis, and tissue homeostasis | |
| 25 | Cancer 1 | Problem set 5 due |
| 26 | Cancer 2 | |
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Exam 3 (Covering Lectures 18–25)
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| 27 | Visualizing life—Dyes and stains | |
| 28 | Visualizing life—Fluorescent proteins | |
| 29 | Cell imaging techniques | |
| 30 | Immunology 1—Diversity, specificity, and B cells | |
| 31 | Immunology 2—Memory, T cells, and autoimmunity | News brief proposal due |
| 32 | Infectious disease, viruses, and bacteria | |
| 33 | Bacteria and antibiotic resistance | |
| 34 | Viruses and anti-viral resistance | Problem set due |
| 35 | Reproductive cloning and embryonic stem cells | |
| 36 | “In the news” | |
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Final Exam (Covering Lectures 1–36)
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